Human SAT1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SAT1
Locus ID	6303
Kit Components	GA104277G1, SAT1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104277G2, SAT1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104277G3, SAT1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002970, NR_027783
Synonyms	DC21; KFSD; KFSDX; SAT; SSAT; SSAT-1
Summary	The protein encoded by this gene belongs to the acetyltransferase family, and is a rate-limiting enzyme in the catabolic pathway of polyamine metabolism. It catalyzes the acetylation of spermidine and spermine, and is involved in the regulation of the intracellular concentration of polyamines and their transport out of cells. Defects in this gene are associated with keratosis follicularis spinulosa decalvans (KFSD). Alternatively spliced transcripts have been found for this gene.[provided by RefSeq, Sep 2009]

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