Human Ryanodine receptor 2 (RYR2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RYR2
Locus ID	6262
Kit Components	GA104244G1, Ryanodine receptor 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104244G2, Ryanodine receptor 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104244G3, Ryanodine receptor 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001035
Synonyms	ARVC2; ARVD2; RyR; RYR-2; VTSIP
Summary	This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia. [provided by RefSeq, Jul 2008]

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