Human Retinoid X Receptor gamma (RXRG) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RXRG
Locus ID	6258
Kit Components	GA104241G1, Retinoid X Receptor gamma gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104241G2, Retinoid X Receptor gamma gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104241G3, Retinoid X Receptor gamma gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001009598, NM_001256570, NM_001256571, NM_006917, NR_033824
Synonyms	NR2B3; RXRC
Summary	This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010]

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