Human RREB1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RREB1
Locus ID	6239
Kit Components	GA104229G1, RREB1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104229G2, RREB1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104229G3, RREB1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001003698, NM_001003699, NM_001003700, NM_001168344, NM_002955
Synonyms	FINB; HNT; LZ321; RREB-1; Zep-1
Summary	The protein encoded by this gene is a zinc finger transcription factor that binds to RAS-responsive elements (RREs) of gene promoters. It has been shown that the calcitonin gene promoter contains an RRE and that the encoded protein binds there and increases expression of calcitonin, which may be involved in Ras/Raf-mediated cell differentiation. Multiple transcript variants encoding several different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

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