Human RP2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RP2
Locus ID	6102
Kit Components	GA104136G1, RP2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104136G2, RP2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104136G3, RP2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006915
Synonyms	DELXp11.3; NM23-H10; NME10; TBCCD2; XRP2
Summary	The RP2 locus has been implicated as one cause of X-linked retinitis pigmentosa. The predicted gene product shows homology with human cofactor C, a protein involved in the ultimate step of beta-tubulin folding. Progressive retinal degeneration may therefore be due to the accumulation of incorrectly-folded photoreceptor or neuron-specific tubulin isoforms followed by progressive cell death [provided by RefSeq, Jul 2008]

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