Human RNF6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	RNF6
Locus ID	6049
Kit Components	GA104122G1, RNF6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA104122G2, RNF6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA104122G3, RNF6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_005977, NM_183043, NM_183044, NM_183045
Synonyms	DKFZp686P0776
Summary	The protein encoded by this gene contains a RING-H2 finger motif. Deletions and mutations in this gene were detected in esophageal squamous cell carcinoma (ESCC), suggesting that this protein may be a potential tumor suppressor. Studies of the mouse counterpart suggested a role of this protein in the transcription regulation that controls germinal differentiation. Multiple alternatively spliced transcript variants encoding the same protein are observed. [provided by RefSeq, Jul 2008]

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