Human Pentraxin 3 (PTX3) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PTX3
Locus ID	5806
Kit Components	GA103950G1, Pentraxin 3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103950G2, Pentraxin 3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103950G3, Pentraxin 3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002852
Synonyms	TNFAIP5; TSG-14
Summary	This gene encodes a member of the pentraxin protein family. The expression of this protein is induced by inflammatory cytokines in response to inflammatory stimuli in several mesenchymal and epithelial cell types, particularly endothelial cells and mononuclear phagocytes. The protein promotes fibrocyte differentiation and is involved in regulating inflammation and complement activation. It also plays a role in angiogenesis and tissue remodeling. The protein serves as a biomarker for several inflammatory conditions. [provided by RefSeq, Jun 2016]

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