Human Prostaglandin F2 alpha Receptor (PTGFR) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PTGFR
Locus ID	5737
Kit Components	GA103901G1, Prostaglandin F2 alpha Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103901G2, Prostaglandin F2 alpha Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103901G3, Prostaglandin F2 alpha Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000959, NM_001039585
Synonyms	FP
Summary	The protein encoded by this gene is member of the G-protein coupled receptor family. This protein is a receptor for prostaglandin F2-alpha (PGF2-alpha), which is known to be a potent luteolytic agent, and may also be involved in modulating intraocular pressure and smooth muscle contraction in uterus. Knockout studies in mice suggest that the interaction of PGF2-alpha with this receptor may initiate parturition in ovarian luteal cells and thus induce luteolysis. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

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