Human Enterokinase (TMPRSS15) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TMPRSS15
Locus ID	5651
Kit Components	GA103830G1, Enterokinase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103830G2, Enterokinase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103830G3, Enterokinase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002772
Synonyms	ENTK; PRSS7
Summary	This gene encodes an enzyme that converts the pancreatic proenzyme trypsinogen to trypsin, which activates other proenzymes including chymotrypsinogen and procarboxypeptidases. The precursor protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. This protein is a member of the trypsin family of peptidases. Mutations in this gene cause enterokinase deficiency, a malabsorption disorder characterized by diarrhea and failure to thrive. [provided by RefSeq, Jul 2008]

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