Human Serglycin (SRGN) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SRGN
Locus ID	5552
Kit Components	GA103748G1, Serglycin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103748G2, Serglycin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103748G3, Serglycin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001321053, NM_001321054, NM_002727, NR_036430
Synonyms	PPG; PRG; PRG1
Summary	This gene encodes a protein best known as a hematopoietic cell granule proteoglycan. Proteoglycans stored in the secretory granules of many hematopoietic cells also contain a protease-resistant peptide core, which may be important for neutralizing hydrolytic enzymes. This encoded protein was found to be associated with the macromolecular complex of granzymes and perforin, which may serve as a mediator of granule-mediated apoptosis. Two transcript variants, only one of them protein-coding, have been found for this gene. [provided by RefSeq, Jul 2010]

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