Human POLE activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	POLE
Locus ID	5426
Kit Components	GA103649G1, POLE gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103649G2, POLE gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103649G3, POLE gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006231
Synonyms	CRCS12; FILS; POLE1
Summary	This gene encodes the catalytic subunit of DNA polymerase epsilon. The enzyme is involved in DNA repair and chromosomal DNA replication. Mutations in this gene have been associated with colorectal cancer 12 and facial dysmorphism, immunodeficiency, livedo, and short stature. [provided by RefSeq, Sep 2013]

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