Human SEPTIN4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SEPTIN4
Locus ID	5414
Kit Components	GA103643G1, SEPTIN4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103643G2, SEPTIN4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103643G3, SEPTIN4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001038704, NM_001198713, NM_001256782, NM_001256822, NM_004574, NM_080415, NM_080416, NM_080417, NR_037155, NR_037156, NR_104196, NR_104197, NM_001363803, NM_001368771, NM_001368772
Synonyms	ARTS; BRADEION; CE5B3; H5; hCDCREL-2; hucep-7; MART; PNUTL2; SEP4
Summary	This gene is a member of the septin family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse, and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is highly expressed in brain and heart. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. One of the isoforms (known as ARTS) is distinct; it is localized to the mitochondria, and has a role in apoptosis and cancer. [provided by RefSeq, Nov 2010]

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