Human PNMT activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PNMT
Locus ID	5409
Kit Components	GA103639G1, PNMT gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103639G2, PNMT gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103639G3, PNMT gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002686, NR_073461
Synonyms	PENT; PNMTase
Summary	The product of this gene catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2012]

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