Human PRRX1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PRRX1
Locus ID	5396
Kit Components	GA103635G1, PRRX1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103635G2, PRRX1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103635G3, PRRX1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006902, NM_022716
Synonyms	AGOTC; PHOX1; PMX1; PRX-1; PRX1
Summary	The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins localized to the nucleus. The protein functions as a transcription co-activator, enhancing the DNA-binding activity of serum response factor, a protein required for the induction of genes by growth and differentiation factors. The protein regulates muscle creatine kinase, indicating a role in the establishment of diverse mesodermal muscle types. Alternative splicing yields two isoforms that differ in abundance and expression patterns. [provided by RefSeq, Jul 2008]

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