Human PMS1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PMS1
Locus ID	5378
Kit Components	GA103631G1, PMS1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103631G2, PMS1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103631G3, PMS1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000534, NM_001128143, NM_001128144, NM_001289408, NM_001289409, NR_110332, NM_001321044, NM_001321045, NM_001321046, NM_001321047, NM_001321048, NM_001321049, NM_001321051
Synonyms	HNPCC3; hPMS1; MLH2; PMSL1
Summary	This gene encodes a protein belonging to the DNA mismatch repair mutL/hexB family. This protein is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in this gene cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also known as Lynch syndrome. [provided by RefSeq, Jul 2008]

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