Human Alpha 2 Antiplasmin (SERPINF2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SERPINF2
Locus ID	5345
Kit Components	GA103604G1, Alpha 2 Antiplasmin gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103604G2, Alpha 2 Antiplasmin gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103604G3, Alpha 2 Antiplasmin gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000934, NM_001165920, NM_001165921
Synonyms	A2AP; AAP; ALPHA-2-PI; API; PLI
Summary	This gene encodes a member of the serpin family of serine protease inhibitors. The protein is a major inhibitor of plasmin, which degrades fibrin and various other proteins. Consequently, the proper function of this gene has a major role in regulating the blood clotting pathway. Mutations in this gene result in alpha-2-plasmin inhibitor deficiency, which is characterized by severe hemorrhagic diathesis. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2009]

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