Human Phospholipase C beta 2 (PLCB2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PLCB2
Locus ID	5330
Kit Components	GA103590G1, Phospholipase C beta 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103590G2, Phospholipase C beta 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103590G3, Phospholipase C beta 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001284297, NM_001284298, NM_001284299, NM_004573
Synonyms	PLC-beta-2
Summary	The protein encoded by this gene is a phosphodiesterase that catalyzes the hydrolysis of phosphatidylinositol 4,5-bisphosphate to the second messengers inositol 1,4,5-trisphosphate (IP3) and diacylglycerol. The encoded protein is activated by G proteins and has been shown to be involved in the type 2 taste receptor signal transduction pathway. In addition, nuclear factor kappa B can regulate the transcription of this gene, whose protein product is also an important regulator of platelet responses. [provided by RefSeq, Jan 2017]

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