Human PI 3 Kinase p85 alpha (PIK3R1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PIK3R1
Locus ID	5295
Kit Components	GA103560G1, PI 3 Kinase p85 alpha gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103560G2, PI 3 Kinase p85 alpha gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103560G3, PI 3 Kinase p85 alpha gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001242466, NM_181504, NM_181523, NM_181524
Synonyms	AGM7; GRB1; IMD36; p85; p85-ALPHA
Summary	Phosphatidylinositol 3-kinase phosphorylates the inositol ring of phosphatidylinositol at the 3-prime position. The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85, 55, or 50 kD. This gene encodes the 85 kD regulatory subunit. Phosphatidylinositol 3-kinase plays an important role in the metabolic actions of insulin, and a mutation in this gene has been associated with insulin resistance. Alternative splicing of this gene results in four transcript variants encoding different isoforms. [provided by RefSeq, Jun 2011]

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