Human SERPINB8 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	SERPINB8
Locus ID	5271
Kit Components	GA103540G1, SERPINB8 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103540G2, SERPINB8 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103540G3, SERPINB8 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001031848, NM_001276490, NM_002640, NM_198833, NM_001348367, NM_001348368, NM_001348369, NM_001348370, NR_145571, NM_001366198
Synonyms	CAP2; PI8
Summary	The protein encoded by this gene is a member of the ov-serpin family of serine protease inhibitors. The encoded protein is produced by platelets and can bind to and inhibit the function of furin, a serine protease involved in platelet functions. In addition, this protein has been found to enhance the mechanical stability of cell-cell adhesion in the skin, and defects in this gene have been associated with an autosomal-recessive form of exfoliative ichthyosis. [provided by RefSeq, Jan 2017]

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