Human PHF1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PHF1
Locus ID	5252
Kit Components	GA103526G1, PHF1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103526G2, PHF1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103526G3, PHF1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002636, NM_024165, NR_027692
Synonyms	hPHF1; MTF2L2; PCL1; PHF2; TDRD19C
Summary	This gene encodes a Polycomb group protein. The protein is a component of a histone H3 lysine-27 (H3K27)-specific methyltransferase complex, and functions in transcriptional repression of homeotic genes. The protein is also recruited to double-strand breaks, and reduced protein levels results in X-ray sensitivity and increased homologous recombination. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009]

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