Human PHEX activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PHEX
Locus ID	5251
Kit Components	GA103525G1, PHEX gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103525G2, PHEX gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103525G3, PHEX gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000444, NM_001282754
Synonyms	HPDR; HPDR1; HYP; HYP1; LXHR; PEX; XLH
Summary	The protein encoded by this gene is a transmembrane endopeptidase that belongs to the type II integral membrane zinc-dependent endopeptidase family. The protein is thought to be involved in bone and dentin mineralization and renal phosphate reabsorption. Mutations in this gene cause X-linked hypophosphatemic rickets. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

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