Human PEX6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PEX6
Locus ID	5190
Kit Components	GA103482G1, PEX6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103482G2, PEX6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103482G3, PEX6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000287, NM_001316313, NR_133009
Synonyms	HMLR2; PAF-2; PAF2; PBD4A; PDB4B; PXAAA1
Summary	This gene encodes a member of the AAA (ATPases associated with diverse cellular activities) family of ATPases. This member is a predominantly cytoplasmic protein, which plays a direct role in peroxisomal protein import and is required for PTS1 (peroxisomal targeting signal 1, a C-terminal tripeptide of the sequence ser-lys-leu) receptor activity. Mutations in this gene cause peroxisome biogenesis disorders of complementation group 4 and complementation group 6. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2015]

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