Human PEX1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PEX1
Locus ID	5189
Kit Components	GA103481G1, PEX1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103481G2, PEX1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103481G3, PEX1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000466, NM_001282677, NM_001282678
Synonyms	HMLR1; PBD1A; PBD1B; ZWS; ZWS1
Summary	This gene encodes a member of the AAA ATPase family, a large group of ATPases associated with diverse cellular activities. This protein is cytoplasmic but is often anchored to a peroxisomal membrane where it forms a heteromeric complex and plays a role in the import of proteins into peroxisomes and peroxisome biogenesis. Mutations in this gene have been associated with complementation group 1 peroxisomal disorders such as neonatal adrenoleukodystrophy, infantile Refsum disease, and Zellweger syndrome. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Sep 2013]

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