Human PDK2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PDK2
Locus ID	5164
Kit Components	GA103461G1, PDK2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103461G2, PDK2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103461G3, PDK2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001199898, NM_001199899, NM_001199900, NM_002611
Synonyms	PDHK2; PDKII
Summary	This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]

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