Human PDGFRL activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PDGFRL
Locus ID	5157
Kit Components	GA103454G1, PDGFRL gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103454G2, PDGFRL gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103454G3, PDGFRL gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_006207
Synonyms	PDGRL; PRLTS
Summary	This gene encodes a protein with significant sequence similarity to the ligand binding domain of platelet-derived growth factor receptor beta. Mutations in this gene, or deletion of a chromosomal segment containing this gene, are associated with sporadic hepatocellular carcinomas, colorectal cancers, and non-small cell lung cancers. This suggests this gene product may function as a tumor suppressor. [provided by RefSeq, Jul 2008]

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