Human PDE8A activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PDE8A
Locus ID	5151
Kit Components	GA103448G1, PDE8A gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103448G2, PDE8A gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103448G3, PDE8A gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001243137, NM_002605, NM_173454, NM_173455, NM_173456, NM_173457
Synonyms	HsT19550
Summary	The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE8 subfamily. This PDE hydrolyzes the second messenger, cAMP, which is a regulator and mediator of a number of cellular responses to extracellular signals. Thus, by regulating the cellular concentration of cAMP, this protein plays a key role in many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2011]

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