Human PDE6 gamma (PDE6G) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PDE6G
Locus ID	5148
Kit Components	GA103445G1, PDE6 gamma gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103445G2, PDE6 gamma gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103445G3, PDE6 gamma gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002602, NR_026872, NM_001365724, NM_001365725, NR_158591
Synonyms	PDEG; RP57
Summary	This gene encodes the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2009]

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