Human PDCD2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	PDCD2
Locus ID	5134
Kit Components	GA103432G1, PDCD2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103432G2, PDCD2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103432G3, PDCD2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001199461, NM_001199462, NM_001199463, NM_001199464, NM_002598, NM_144781, NM_001363655
Synonyms	RP8; ZMYND7
Summary	This gene encodes a nuclear protein expressed in a variety of tissues. Expression of this gene has been shown to be repressed by B-cell CLL/lymphoma 6 (BCL6), a transcriptional repressor required for lymph node germinal center development, suggesting that BCL6 regulates apoptosis by its effects on this protein. Alternative splicing results in multiple transcript variants and pseudogenes have been identified on chromosomes 9 and 12. [provided by RefSeq, Dec 2010]

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