Human P2Y2 (P2RY2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	P2RY2
Locus ID	5029
Kit Components	GA103358G1, P2Y2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103358G2, P2Y2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103358G3, P2Y2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002564, NM_176071, NM_176072
Synonyms	HP2U; P2RU1; P2U; P2U1; P2UR; P2Y2; P2Y2R
Summary	The product of this gene belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, found on many cell types, is activated by ATP and UTP and is reported to be overexpressed on some cancer cell types. It is involved in many cellular functions, such as proliferation, apoptosis and inflammation. Three transcript variants encoding the same protein have been identified for this gene. [provided by RefSeq, Mar 2013]

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