Human ORC5L (ORC5) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ORC5
Locus ID	5001
Kit Components	GA103335G1, ORC5L gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103335G2, ORC5L gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103335G3, ORC5L gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001197292, NM_002553, NM_181747
Synonyms	ORC5L; ORC5P; ORC5T
Summary	The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Oct 2010]

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