Human Ornithine Decarboxylase (ODC1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ODC1
Locus ID	4953
Kit Components	GA103308G1, Ornithine Decarboxylase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103308G2, Ornithine Decarboxylase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103308G3, Ornithine Decarboxylase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001287188, NM_001287189, NM_001287190, NM_002539
Synonyms	ODC
Summary	This gene encodes the rate-limiting enzyme of the polyamine biosynthesis pathway which catalyzes ornithine to putrescine. The activity level for the enzyme varies in response to growth-promoting stimuli and exhibits a high turnover rate in comparison to other mammalian proteins. Originally localized to both chromosomes 2 and 7, the gene encoding this enzyme has been determined to be located on 2p25, with a pseudogene located on 7q31-qter. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2013]

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