Human INPP5F (OCRL) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	OCRL
Locus ID	4952
Kit Components	GA103307G1, INPP5F gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103307G2, INPP5F gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103307G3, INPP5F gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000276, NM_001318784, NM_001587
Synonyms	INPP5F; LOCR; NPHL2; OCRL-1; OCRL1
Summary	This gene encodes an inositol polyphosphate 5-phosphatase. This protein is involved in regulating membrane trafficking and is located in numerous subcellular locations including the trans-Golgi network, clathrin-coated vesicles and, endosomes and the plasma membrane. This protein may also play a role in primary cilium formation. Mutations in this gene cause oculocerebrorenal syndrome of Lowe and also Dent disease. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]

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