Human ornithine aminotransferase (OAT) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	OAT
Locus ID	4942
Kit Components	GA103301G1, ornithine aminotransferase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103301G2, ornithine aminotransferase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103301G3, ornithine aminotransferase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000274, NM_001171814, NM_001322965, NM_001322966, NM_001322967, NM_001322968, NM_001322969, NM_001322970, NM_001322971, NM_001322974
Synonyms	GACR; HOGA; OATASE; OKT
Summary	This gene encodes the mitochondrial enzyme ornithine aminotransferase, which is a key enzyme in the pathway that converts arginine and ornithine into the major excitatory and inhibitory neurotransmitters glutamate and GABA. Mutations that result in a deficiency of this enzyme cause the autosomal recessive eye disease Gyrate Atrophy. Alternatively spliced transcript variants encoding different isoforms have been described. Related pseudogenes have been defined on the X chromosome. [provided by RefSeq, Jan 2010]

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