Human TrkA (NTRK1) activation kit by CRISPRa

CAT#: GA103281

NTRK1 CRISPRa kit - CRISPR gene activation of human neurotrophic receptor tyrosine kinase 1



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CNY 12255.00


货期*
4周

规格
    • 1 kit

Product images

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol NTRK1
Locus ID 4914
Kit Components

GA103281G1, TrkA gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA103281G2, TrkA gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA103281G3, TrkA gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_001007204, NM_001007792, NM_001012331, NM_002529
Synonyms MTC; p140-TrkA; TRK; Trk-A; TRK1; TRKA
Summary This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. [provided by RefSeq, Jul 2008]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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