Human Neuromedin B (NMB) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NMB
Locus ID	4828
Kit Components	GA103220G1, Neuromedin B gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103220G2, Neuromedin B gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103220G3, Neuromedin B gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_021077, NM_205858
Synonyms	MGC2277; MGC3936; MGC17211
Summary	This gene encodes a member of the bombesin-like family of neuropeptides, which negatively regulate eating behavior. The encoded protein may regulate colonic smooth muscle contraction through binding to its cognate receptor, the neuromedin B receptor (NMBR). Polymorphisms of this gene may be associated with hunger, weight gain and obesity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2015]

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