Human Nance Horan Syndrome Protein (NHS) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NHS
Locus ID	4810
Kit Components	GA103209G1, Nance Horan Syndrome Protein gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103209G2, Nance Horan Syndrome Protein gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103209G3, Nance Horan Syndrome Protein gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001136024, NM_001291867, NM_001291868, NM_198270
Synonyms	CTRCT40; CXN; SCML1
Summary	This gene encodes a protein containing four conserved nuclear localization signals. The encoded protein functions in eye, tooth, craniofacial and brain development, and it can regulate actin remodeling and cell morphology. Mutations in this gene have been shown to cause Nance-Horan syndrome, and also X-linked cataract-40. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, May 2014]

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