Human Neurofilament (NEFM) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NEFM
Locus ID	4741
Kit Components	GA103164G1, Neurofilament gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103164G2, Neurofilament gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103164G3, Neurofilament gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001105541, NM_005382
Synonyms	NEF3; NF-M; NFM
Summary	Neurofilaments are type IV intermediate filament heteropolymers composed of light, medium, and heavy chains. Neurofilaments comprise the axoskeleton and functionally maintain neuronal caliber. They may also play a role in intracellular transport to axons and dendrites. This gene encodes the medium neurofilament protein. This protein is commonly used as a biomarker of neuronal damage. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008]

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