Human NCBP1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NCBP1
Locus ID	4686
Kit Components	GA103117G1, NCBP1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103117G2, NCBP1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103117G3, NCBP1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002486, NM_001351504, NM_001351505, NM_001351506, NM_001351507
Synonyms	CBP80; NCBP; Sto1
Summary	The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. [provided by RefSeq, Jul 2008]

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