Human NAGLU activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NAGLU
Locus ID	4669
Kit Components	GA103102G1, NAGLU gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103102G2, NAGLU gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103102G3, NAGLU gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000263
Synonyms	MPS-IIIB; MPS3B; NAG; UFHSD
Summary	This gene encodes an enzyme that degrades heparan sulfate by hydrolysis of terminal N-acetyl-D-glucosamine residues in N-acetyl-alpha-D-glucosaminides. Defects in this gene are the cause of mucopolysaccharidosis type IIIB (MPS-IIIB), also known as Sanfilippo syndrome B. This disease is characterized by the lysosomal accumulation and urinary excretion of heparan sulfate. [provided by RefSeq, Jul 2008]

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