Human n-Myc (MYCN) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MYCN
Locus ID	4613
Kit Components	GA103057G1, n-Myc gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103057G2, n-Myc gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103057G3, n-Myc gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001293228, NM_001293231, NM_001293233, NM_005378
Synonyms	bHLHe37; MODED; N-myc; NMYC; ODED
Summary	This gene is a member of the MYC family and encodes a protein with a basic helix-loop-helix (bHLH) domain. This protein is located in the nucleus and must dimerize with another bHLH protein in order to bind DNA. Amplification of this gene is associated with a variety of tumors, most notably neuroblastomas. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jun 2014]

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