Human Mannose Receptor (MRC1) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MRC1
Locus ID	4360
Kit Components	GA102970G1, Mannose Receptor gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102970G2, Mannose Receptor gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102970G3, Mannose Receptor gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_002438
Synonyms	bA541I19.1; CD206; CLEC13D; CLEC13DL; MMR; MRC1L1
Summary	The recognition of complex carbohydrate structures on glycoproteins is an important part of several biological processes, including cell-cell recognition, serum glycoprotein turnover, and neutralization of pathogens. The protein encoded by this gene is a type I membrane receptor that mediates the endocytosis of glycoproteins by macrophages. The protein has been shown to bind high-mannose structures on the surface of potentially pathogenic viruses, bacteria, and fungi so that they can be neutralized by phagocytic engulfment.[provided by RefSeq, Sep 2015]

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