Human Mannose Phosphate Isomerase (MPI) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	MPI
Locus ID	4351
Kit Components	GA102961G1, Mannose Phosphate Isomerase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102961G2, Mannose Phosphate Isomerase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102961G3, Mannose Phosphate Isomerase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001289155, NM_001289156, NM_001289157, NM_002435, NM_001330372
Synonyms	CDG1B; PMI; PMI1
Summary	Phosphomannose isomerase catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate and plays a critical role in maintaining the supply of D-mannose derivatives, which are required for most glycosylation reactions. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]

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