Human CD200 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	CD200
Locus ID	4345
Kit Components	GA102959G1, CD200 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102959G2, CD200 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102959G3, CD200 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001004196, NM_001004197, NM_001318826, NM_001318828, NM_001318830, NM_005944, NM_001365851, NM_001365852, NM_001365853, NM_001365854, NR_158642, NM_001365855
Synonyms	MOX1; MOX2; MRC; OX-2
Summary	This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]

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