Human TRPM1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	TRPM1
Locus ID	4308
Kit Components	GA102931G1, TRPM1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102931G2, TRPM1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102931G3, TRPM1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001252020, NM_001252024, NM_001252030, NM_002420, N42519
Synonyms	CSNB1C; LTRPC1; MLSN1
Summary	This gene encodes a member of the transient receptor potential melastatin subfamily of transient receptor potential ion channels. The encoded protein is a calcium permeable cation channel that is expressed in melanocytes and may play a role in melanin synthesis. Specific mutations in this gene are the cause autosomal recessive complete congenital stationary night blindness-1C. The expression of this protein is inversely correlated with melanoma aggressiveness and as such it is used as a prognostic marker for melanoma metastasis. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Oct 2011]

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