Human NBR1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	NBR1
Locus ID	4077
Kit Components	GA102769G1, NBR1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102769G2, NBR1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102769G3, NBR1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001291571, NM_001291572, NM_005899, NM_031858, NM_031862
Synonyms	1A1-3B; IAI3B; M17S2; MIG19
Summary	The protein encoded by this gene was originally identified as an ovarian tumor antigen monitored in ovarian cancer. The encoded protein contains a B-box/coiled-coil motif, which is present in many genes with transformation potential. It functions as a specific autophagy receptor for the selective autophagic degradation of peroxisomes by forming intracellular inclusions with ubiquitylated autophagic substrates. This gene is located on a region of chromosome 17q21.1 that is in close proximity to the BRCA1 tumor suppressor gene. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Apr 2014]

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