Human M6PR activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	M6PR
Locus ID	4074
Kit Components	GA102767G1, M6PR gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102767G2, M6PR gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102767G3, M6PR gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001207024, NM_002355
Synonyms	CD-MPR; MPR-46; MPR 46; MPR46; SMPR
Summary	This gene encodes a member of the P-type lectin family. P-type lectins play a critical role in lysosome function through the specific transport of mannose-6-phosphate-containing acid hydrolases from the Golgi complex to lysosomes. The encoded protein functions as a homodimer and requires divalent cations for ligand binding. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, May 2011]

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