Human LY6H activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LY6H
Locus ID	4062
Kit Components	GA102756G1, LY6H gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102756G2, LY6H gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102756G3, LY6H gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001130478, NM_001135655, NM_002347
Synonyms	NMLY6
Summary	Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro inhibits alpha-3:beta-4-containing nAChRs maximum response. May play a role in the intracellular trafficking of alpha-7-containing nAChRs and may inhibit their expression at the cell surface. Seems to inhibit alpha-7/CHRNA7 signaling in hippocampal neurons.[UniProtKB/Swiss-Prot Function]

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