Human Lipoprotein lipase (LPL) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	LPL
Locus ID	4023
Kit Components	GA102727G1, Lipoprotein lipase gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102727G2, Lipoprotein lipase gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102727G3, Lipoprotein lipase gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000237
Synonyms	HDLCQ11; LIPD
Summary	LPL encodes lipoprotein lipase, which is expressed in heart, muscle, and adipose tissue. LPL functions as a homodimer, and has the dual functions of triglyceride hydrolase and ligand/bridging factor for receptor-mediated lipoprotein uptake. Severe mutations that cause LPL deficiency result in type I hyperlipoproteinemia, while less extreme mutations in LPL are linked to many disorders of lipoprotein metabolism. [provided by RefSeq, Jul 2008]

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