Human Cytokeratin 16 (KRT16) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KRT16
Locus ID	3868
Kit Components	GA102625G1, Cytokeratin 16 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102625G2, Cytokeratin 16 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102625G3, Cytokeratin 16 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_005557
Synonyms	CK16; FNEPPK; K1CP; K16; KRT16A; NEPPK; PC1
Summary	The protein encoded by this gene is a member of the keratin gene family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. Most of the type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains and are clustered in a region of chromosome 17q12-q21. This keratin has been coexpressed with keratin 14 in a number of epithelial tissues, including esophagus, tongue, and hair follicles. Mutations in this gene are associated with type 1 pachyonychia congenita, non-epidermolytic palmoplantar keratoderma and unilateral palmoplantar verrucous nevus. [provided by RefSeq, Jul 2008]

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