Human Cytokeratin 2 (KRT2) activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	KRT2
Locus ID	3849
Kit Components	GA102611G1, Cytokeratin 2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102611G2, Cytokeratin 2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102611G3, Cytokeratin 2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_000423
Synonyms	CK-2e; K2e; KRT2A; KRT2E; KRTE
Summary	The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. This type II cytokeratin is expressed largely in the upper spinous layer of epidermal keratinocytes and mutations in this gene have been associated with bullous congenital ichthyosiform erythroderma. The type II cytokeratins are clustered in a region of chromosome 12q12-q13. [provided by RefSeq, Jul 2008]

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